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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
22.73
Human Site:
T75
Identified Species:
33.33
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
T75
K
H
G
E
K
L
Y
T
G
L
R
E
V
V
T
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
N76
V
V
T
E
H
L
I
N
K
V
R
E
D
V
L
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
N73
K
V
R
E
D
V
L
N
S
L
N
N
N
F
L
Dog
Lupus familis
XP_534586
746
86477
N73
K
V
R
E
D
V
L
N
S
L
N
N
N
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
T75
K
H
G
E
K
L
Y
T
G
L
R
E
V
V
T
Rat
Rattus norvegicus
Q9JJ31
780
90872
H83
A
Q
A
R
V
L
S
H
Q
D
D
T
A
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
Chicken
Gallus gallus
XP_422620
768
88957
T75
K
H
G
E
K
L
Y
T
G
L
R
E
V
V
T
Frog
Xenopus laevis
Q6DE95
768
88933
T75
K
H
G
E
K
L
Y
T
G
L
R
E
V
V
T
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
T73
K
H
G
E
K
L
Y
T
G
L
R
E
V
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
D80
L
V
G
K
K
L
Y
D
R
L
E
Q
F
L
K
Honey Bee
Apis mellifera
XP_625079
767
89385
T72
K
Y
G
E
R
L
Y
T
G
L
K
E
V
V
T
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
N72
K
H
G
E
R
L
Y
N
G
L
K
D
V
I
Q
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
I29
N
D
H
Q
T
A
M
I
M
I
R
D
I
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
P80
Y
I
N
S
T
V
L
P
A
L
R
E
K
H
D
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
Q75
R
L
K
D
Y
L
I
Q
K
L
A
L
L
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
33.3
20
20
N.A.
100
6.6
N.A.
0
100
100
100
N.A.
33.3
80
60
6.6
P-Site Similarity:
100
40
26.6
26.6
N.A.
100
13.3
N.A.
0
100
100
100
N.A.
53.3
100
86.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
7
0
0
7
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
13
0
0
7
0
7
7
13
7
0
7
% D
% Glu:
0
0
0
63
0
0
0
0
0
0
7
50
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
13
0
% F
% Gly:
0
0
50
0
0
0
0
0
44
0
0
0
0
0
0
% G
% His:
0
38
7
0
7
0
0
7
0
0
0
0
0
7
0
% H
% Ile:
0
7
0
0
0
0
13
7
0
7
0
0
7
7
0
% I
% Lys:
57
0
7
7
38
0
0
0
13
0
13
0
7
0
7
% K
% Leu:
7
7
0
0
0
69
19
0
0
75
0
7
7
19
25
% L
% Met:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
7
% M
% Asn:
7
0
7
0
0
0
0
25
0
0
13
13
13
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
7
0
0
0
7
7
0
0
7
0
0
7
% Q
% Arg:
7
0
13
7
13
0
0
0
7
0
50
0
0
7
0
% R
% Ser:
0
0
0
7
0
0
7
0
13
0
0
0
0
0
0
% S
% Thr:
0
0
7
0
13
0
0
38
0
0
0
7
0
0
38
% T
% Val:
7
25
0
0
7
19
0
0
0
7
0
0
44
44
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
7
0
50
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _